Autoimmunity can cause many symptoms that vary from person to person. Parts of the body that get affected are skin, kidneys, heart and vascular system, connective tissues, muscoloskeletal system, and other organs. The immune system is the primary facilitator of lupus, thus treatment is needed to successfully target immune cells. Conventional medicines rely on immune suppression to accomplish this goal, which leave patients open to deadly infections and a lot of side effects. New medical therapies are developing for lupus such as monoclonal antibodies and stem cell therapy. Vitamin D may be a huge missing link in almost all autoimmune diseases, including lupus. Vitamin D helps with the activity of immune cells, and there has been found that a Vitamin D deficiency is huge in people with Lupus.